CBD is a fat-soluble cannabinoid that is growing in popularity. For bioavailability and for the sake of making CBD-infused products, it is important to know how to make “water-soluble” CBD. Here, we describe solubility and solutions for making water-soluble CBD, such as by using a CBD nanoemulsion.
The difference between nanoemulsions and microemulsions, however, is not so much one of size as of their functional features and how they are made. While both types of emulsion require similar ingredients — oil, water and one or more surfactants — microemulsions, which are thermodynamically stable, will spontaneously self-assemble. In contrast, nanoemulsions are made using technological processes like mechanical shearing or sonication to create droplets with wavelengths shorter than the wavelengths of visible light (and therefore seen by human eyes as clear).